Scientific Imaging & Research

Observe and measure fast, transient phenomena

Resolve fluorescence events, particle motion and rapid flow with microsecond-scale temporal precision and sparse, time-stamped data.

Explore published research and experimental systems using Prophesee Event-Based Vision across microscopy, microfluidics, biomedical research and fluid measurement.

Scientific imaging and research with Event-Based Vision

Event-Based Vision for scientific measurement

Resolve rapid transitions, motion and transient events

Microsecond-scale

temporal precision

Observe relevant change across bright and dark regions

>120 dB

dynamic range

Support real-time measurement and experimental feedback

<1 ms

latency

Record relevant visual changes without repeated full frames

Sparse output

change-driven data

Representative performance across selected Prophesee Event-Based Vision technologies. Actual performance depends on the selected technology, configuration and experimental conditions.

Single-molecule localization microscopy

Event-based sensing records fluorescence blinking as precisely time-stamped events, allowing individual emitters to be localized without acquiring a continuous sequence of complete frames.

The published Eve-SMLM method demonstrated super-resolution fluorescence imaging with improved acquisition speed under high-density blinking conditions, where overlapping emitters can challenge conventional frame-based methods.

≈25 nm

Reconstructed spatial resolution

10× faster

Acquisition versus frame-based cameras

Conventional fluorescence image of the cytoskeleton, about 250 nm resolution
Resolution ≈250 nm
Super-resolved single-molecule localization image of the cytoskeleton, about 25 nm resolution
Resolution ≈25 nm

Conventional fluorescence image (≈250 nm) compared with single-molecule localization (≈25 nm). Izeddin et al., PLoS One 2011.

Related research areas

  • Single-molecule localization microscopy
  • Fluorescence microscopy
  • Super-resolution imaging
  • Molecular localization
  • Biological imaging

Microfluidics and particle analysis

Precisely time-stamped event data enables particles to be detected, tracked and measured as they move through microchannels at high velocity.

Researchers from the Universities of Glasgow, Heriot-Watt and Strathclyde applied Event-Based Vision to bright-field and fluorescence observation using a standard microscope-based configuration.

Down to 1 μm

Particle diameter

Up to 1.54 m/s

Measured fluid velocity

Micro-particle tracking in a microfluidic device using an event camera.

Related research areas

  • Microfluidics
  • Micro-particle tracking
  • Micro-PIV
  • Particle velocity measurement
  • Fluorescence imaging
  • Flow analysis

Biomedical research and experimental vision systems

Event-Based Vision is also being investigated for time-resolved biomedical measurement, particle classification and experimental visual-assistance systems.

Label-free imaging flow cytometry

Researchers at Ghent University used event-based imaging to capture the changing diffraction patterns generated by particles moving through a flow-cytometry system.

In the reported experiment, the sparse temporal signatures supported particle classification with lower error and reduced execution time compared with the stated CMOS-based method.

<2%

Classification error*

Sub-millisecond

Processing latency

Diffraction patterns of particles in a flow-cytometry system captured with event-based imaging

Related research areas

  • Imaging flow cytometry
  • Label-free particle classification
  • Biological-particle analysis
  • Time-resolved imaging
  • Inline measurement

Sight restoration through optogenetic stimulation

Prophesee’s event-based sensing was integrated into specialized goggles that captured changes in the visual scene and converted them into light patterns used alongside optogenetic therapy.

The initial single-patient study reported partial recovery of visual function in a participant with late-stage retinitis pigmentosa.

Nature Medicine

Peer-reviewed publication

First case report

Partial recovery of visual function using the combined system

Related research areas

  • Optogenetics
  • Visual prostheses
  • Assistive vision
  • Retinal research
  • Neuromorphic biomedical systems

Continuous cell and contamination monitoring

Video courtesy of Cambridge Consultants.

Cambridge Consultants developed PureSentry, an experimental system combining event-based imaging and AI models to detect, track and classify cells and microbial contaminants in flowing samples.

The project explores continuous, label-free visual analysis in cell and gene-therapy research and manufacturing environments.

Related research areas

  • Cell monitoring
  • Microbial contamination detection
  • Label-free analysis
  • Cell-therapy research
  • Continuous biological measurement

Flow visualization and velocimetry

Event-Based Vision captures illuminated tracer particles as continuous, time-stamped trajectories from which evolving velocity fields can be reconstructed.

Researchers at the DLR Institute of Propulsion Technology demonstrated event-based imaging velocimetry across water and air flows, including turbulent conditions and measurements close to surfaces where reflected illumination can complicate frame-based acquisition.

100 mm

Demonstrated field-of-view width

<1 W

Laser power used in the documented setup

Turbulent flow in a water tank reconstructed from captured event data.

Related research areas

  • Event-based imaging velocimetry
  • Particle image velocimetry
  • Particle tracking velocimetry
  • Fluid dynamics
  • Turbulent flow
  • Air and water-flow measurement

Build on the research

Evaluate Event-Based Vision within your own experimental configuration using hardware, software and technical resources from Prophesee.

Embra HD

An Event-Based Vision exploration kit featuring a compact, industrial-grade USB camera for acquiring event data, evaluating experimental configurations and prototyping.

Hearth®

Prophesee’s intelligence and software platform for developing, integrating and deploying Event-Based Vision processing and applications.

Developer resources

Access documentation, code examples and technical guidance for camera configuration, event-data acquisition and processing.

Inventors Community

Discover experimental projects developed by researchers, engineers and inventors using Prophesee technology.